For you guys with Hypex modules and PEQ, why not program in the opposite of the FR plot (HF only) posted above to bring the amplifier up to flat at 20KHz and see if you can hear a difference on content when switched in and out?
Not a direct answer but I have some related anecdotal experience.
In a new inexpensive pre/amp combo (which was fine for HT), I was getting annoying tizziness at the high end for music. So decided to do some experiments with PEQ varying cut-off frequencies and attenuation using a shelf filter (which has less artifacts than a narrow filter). When I did the raw measurement, I realized that there was a pronounced hump starting around 12khz and going up to about 18khz before dipping down.
I could take out that tizziness with some attenuation after 12khz (most of it to take out the hump to be flatter) but to arrive at that number, I tried a number of values to find the optimal (i.e., minimal attenuation needed). Using Equalizer APO, it is trivial to adjust in 0.1db increments and do quick A/B testing (not blind). I could not hear much of a change in the resulting sound (in this case, losing tizziness) for less than about 0.8db difference one way or the other.
But like detecting pitch difference, it also depended on the delta magnitude. So, if I went up in steps of 0.1, it was very hard to detect a difference with the preceding but if I jumped back and forth at least 0.8db in one step, I could hear a difference.
In terms of what this means in practice, my conclusions would be that this varies a lot from person to person (both the minimum delta and the frequency sensitivity). If you have been listening to music with less than 1db attenuation at those levels (rather than switching back and forth), you will likely not miss anything. However, that 1db difference may make the difference between something sounding too bright or tizzy or or too dull or just right depending on your sensitivity and that may become apparent only in A/B testing!
Note that because of the interaction with speakers and the room, a flat amp response may not necessarily sound "right", so it is quite possible that an amp which has a roll-off actually sounds good to you coming out of your speakers than one that is flat and vice versa.
So t
o be flat or not to be flat becomes a rather academic issue and difficult to predict based on measurements alone.
Someone should come up with the math and a tool for combining speaker and amp measurements and showing an effective curve with that combo. That might help choose the right combination if you have one of them and looking for the other.