The Output stage of the Class D chip is switched on or of so with higher voltage it has more "Gain"Can anyone explain the higher noise with the 48v PSU? At the risk of saying something silly: Is the gain different?
This is Compensate by Shorter on time of the output switch.
Since the switching time in a class d is the analog part it has some noise and if time gets shorter the noises gets more significant compared to the on time.
Also the output inductor (and caps) get more ripple this makes them more "noisy" and more non linear